Innovation and Metastability: a Systems Model

The culture trap is the tendency to put cultural markers and habits above the demands of reason or compassion.It can reduce receptivity to new ideas and trigger Phoenix Cycles of catastrophe and Everything Else renaissance.System research is then complicated by the historiographic problem of continuity and change, because there are no objective cri

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Nutritional strategies to optimise musculoskeletal health for fall and fracture prevention: Looking beyond calcium, vitamin D and protein

Falls and osteoporotic fractures are a major public health problem, particularly among older adults.A third of individuals aged 65 years and over fall at least once each year, with up to 20 % of these resulting in serious injury, including fracture.In conjunction with regular exercise, the importance of diet for musculoskeletal health has largely f

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Stress-induced chaperones: a first line of defense against the powerful oxidant hypochlorous acid [version 1; peer review: 4 approved]

Hypochlorous acid (HOCl; bleach) is a powerful weapon used by our immune system to eliminate invading bacteria.Yet the way HOCl actually kills bacteria and how they defend themselves pussy-masturbators from its oxidative action have only started to be uncovered.As this molecule induces both protein oxidation and aggregation, bacteria need concerted

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